The XDRO registry is a product of collaboration between IDPH, Medical Research Analytics and Informatics Alliance (MRAIA), and the Chicago CDC Prevention Epicenter.

Carbapenem-resistant Enterobacterales (CRE) are extensively drug resistant organisms (XDROs) that have few treatment options and high mortality rates. CRE are increasingly detected among patients in Illinois, including in acute and long term care healthcare facilities.

In response to the CRE public health threat, the Illinois Department of Public Health (IDPH) has guided development of an infection control tool called the XDRO registry. The purpose of the XDRO registry is two-fold:

  1. Improve CRE surveillance: The first CRE-positive culture per patient stay must be reported to the XDRO registry.
  2. Improve inter-facility communication: Healthcare facilities can query the XDRO registry to see whether a patient has been previously reported as CRE-positive.

For access to the XDRO registry, click here